MYC amplifies mitotic perturbations elicited by LXY18 to enable synthetic lethality

Research Article – bioRxiv 2023.11.07.565938; DOI: 10.1101/2023.11.07.565938

Characterization of mitotic phenotypes associated with a MYC synthetic lethal compound

Research Article – Journal of Pharmacy and Pharmacology Research 7 (2023): 177-191

In-vitro metabolism of LXY18, an orally available, potent blocker of AURKB relocation in mitosis

Research Article – Journal of Pharmaceutical and Biomedical Analysis (2023), 115415

2-Phenoxy-3, 4′-bipyridine derivatives inhibit AURKB-dependent mitotic processes by disrupting its localization

Research Article – European Journal of Medicinal Chemistry (2022), 114904

The Effect of Circumscribed Exposure to the Pan-Aurora Kinase Inhibitor VX-680 on Proliferating Euploid Cells

Research Article – International Journal of Molecular Sciences (2022), 23 (20), 12104

The Phytochemical, Corynoline, Diminishes Aurora Kinase B Activity to Induce Mitotic Defect and Polyploidy

Research Article – Biomedicine & Pharmacotherapy (2022), DOI: 10.1016/j.biopha.2022.112645

The Phytochemical Scoulerine Inhibits Aurora Kinase Activity to Induce Mitotic and Cytokinetic Defects

Research Article – Journal of Natural Products (2021), DOI: 10.1021/acs.jnatprod.1c00429

Mini-library approach delivers an arsenal in drug development pipeline

Article – Drug Discovery World (2021), 22 (3): 64-67

Emerging Strategies to Attack Polyploid Cancer Cells

Review Article – Journal of Cellular Immunology (2020), 2 (4):199-206

Pro-survival Bcl-2 proteins are modifiers of MYC-VX-680 synthetic lethality

Commentary – Journal of Cellular Immunology (2020), 2 (5):227-232