Origins, Affiliation & Governance

The J. Michael Bishop Institute of Cancer Research was established by Dun Yang to pursue basic research on the constraints that govern malignant persistence, with initial emphasis on MYC-driven, high-demand malignant regimes, using disciplined phenotypic measurement and testable standards of interpretation. Through this work, the Institute developed and now advances Architectural Oncology as a structured, falsifiable research program. JMBI is governed by the Canon and by explicit admissibility and falsifiability conditions that define what counts as evidence and which interpretations are permitted. The Institute is institutionally affiliated with Anticancer Bioscience: JMBI maintains the framework and evidence standards, while ACB leads translational programs that may be informed by those standards.

Architectural Oncology is a proposed framework; its claims are bounded by explicit admissibility rules and refined as evidence accumulates.