The formal body of work that defines and constraints the interpretation of Architectural Oncology.
The Canon comprises the primary publications in which Architectural Oncology is formally stated and delimited. Together, these works establish first principles, admissible interpretations, and conditions of validity. They are not summaries or reviews; they function as the discipline’s primary references.
Interpretation of Architectural Oncology is to be made with reference to this body of work. Selective citation, partial reading, or extraction of concepts outside their stated assumptions and boundary conditions is discouraged.
How to Read This Work
The canonical publications are structured as a coherent system: concepts introduced in one work are defined, constrained, and extended in others. Individual terms or sections should therefore not be treated as independent assertions.
A recommended reading order is provided and should be followed with attention to stated definitions, assumptions, and boundary conditions. Disagreement with conclusions is admissible; reinterpretation that violates stated constraints is not.
The Monograph Trilogy
The Monograph Trilogy provides the formal foundation of Architectural Oncology and defines the scope of the discipline.
- Volume I — ArchêEstablishes first principles, terminology, and the architectural interpretation of malignant persistence.
- Volume II — AitiaPresents mechanistic demonstrations across biological scales, linking architectural feasibility to architecture-wide behavior.
- Volume III — PraxisArticulates translational and clinical logic derived from architectural constraints, including implications for therapeutic intervention.
Together, these volumes define the conceptual, mechanistic, and translational structure of the field.
The SYMPLEX Monograph
The SYMPLEX Monograph formalizes the experimental architecture used to test architectural claims under oncogenic load. It defines SYMPLEX as a recursive evaluation regime, specifies admissible evidence, and delineates limits of inference.
This work governs how architectural executability is experimentally assessed and how stress-test conclusions are to be interpreted.
Peer-Reviewed Foundations
Peer-reviewed publications anchor Architectural Oncology within the broader scientific literature. These works document experimental observations, methodological advances, and translational findings that support, test, or refine architectural claims.
They are intended to be read in conjunction with the monographs and interpreted within the constraints established by the Canon.
Role of the Canon
The Canon exists to ensure coherence, falsifiability, and interpretive discipline—defining what Architectural Oncology is, what it is not, and how its claims are to be evaluated.