Architectural collapse serves as the discriminating readout. Both persistence that remains executable under stress and persistence that is broken are carried forward to refine hypotheses and sharpen subsequent tests.
SYMPLEX operates as a recursive filter on admissible architectural claims. Each stress-test cycle narrows the set of admissible explanations, and informs the design of subsequent perturbations. Claims that fail to withstand repeated adversarial testing under oncogenic load are excluded, irrespective of mechanistic plausibility or prior expectation.