SYMPLEX™ Drug Discovery Platform

SYMPLEX™ is a self-renewing discovery engine that generates, screens, and optimizes MYC-SL drug candidates with novel mechanisms.

  • GUNS-DF (General utility new scaffold-drug fragment)
    Diverse and regenerative chemical scaffolds and fragments tailored to MYC biology

  • MIPS (Mechanism-Informed Phenotypic Screening)
    Systematic cancer cell survival dependency and phenotypic analysis technology

  • DrugGPT (An AI Drug Discovery & Integration System)
    Integration and analysis of generated biological and chemical structure data to optimize next-generation molecules

 Systematic discovery of MYC-SL drug candidates through:

  • Design: Rational compound design across diverse scaffolds

  • Test: Biological screening in MYC-relevant systems

  • Learn: Data-driven optimization and mechanism refinement

  • Outcome: Discovery of compounds with mechanisms distinct from prior MYC approaches

Biological Phenotype Output